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Zepbound vs Wegovy: The Quick Answer In the SURMOUNT-5 head-to-head trial, Zepbound (tirzepatide) produced an average weight loss of 20.2% versus Wegovys (semaglutide) 13.7% over 72 weeks a 47% greater relative weight loss

Decreasing glucagon secretion when blood sugar is high

But distinguishing between expected side effects and new symptoms that require medical attention is critical for staying safe on your protocol

These elements work together to help you achieve and maintain success

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With the right approachincluding gentle nutrition, hydration, and physical activityyou can reduce side effects and support a healthier, more sustainable transformation